Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100268 | 0.64 | — | — | |
| SCHEMBL12498079 | 0.64 | OR51E2 (0.31) | OR51E2 | |
| SCHEMBL21886264 | 0.63 | UHRF1 (0.30) | UHRF1 | |
| SCHEMBL20925334 | 0.63 | — | — | |
| SCHEMBL8866832 | 0.62 | OR51E2 (0.47) | UHRF1LMNAHSD17B10OR51E2 | |
| SCHEMBL14529354 | 0.61 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL15888431 | 0.61 | PNMT (0.32) | — | |
| SCHEMBL5056719 | 0.59 | OR51E2 (0.39) | LMNAHSD17B10OR51E2 | |
| SCHEMBL20171032 | 0.58 | — | — | |
| SCHEMBL1777396 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663292-A1 | DIPHENYLMETHANE DERIVATIVE IN CRYSTALLINE FORM | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-06-10 | — | — | EP | disclosed |
| US-9975902-B2 | Compounds for the inhibition of cyclophilins and uses thereof | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |