SCHEMBL21886264

SCHEMBL21886264

C/C1=C/C2=C(NC=CC2)NCCC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20169627 0.63 UHRF1 (0.32) UHRF1
SCHEMBL22179147 0.55
SCHEMBL8866835 0.52 OR51E2 (0.43) UHRF1
SCHEMBL1777396 0.52
SCHEMBL431692 0.52
SCHEMBL10013883 0.52
SCHEMBL6340609 0.52
SCHEMBL14529354 0.51 LMNA (0.30)
SCHEMBL15888431 0.51 PNMT (0.32)
SCHEMBL11981462 0.51 KDM4E (0.44) UHRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3141548-B1 PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES VERTEX PHARMA (US) 2020-04-08 EP disclosed