Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418572 | 0.82 | NPSR1 (0.47) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL16418545 | 0.79 | HCAR2 (0.38) | — | |
| SCHEMBL20169647 | 0.69 | ALDH1A1 (0.37) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL30678327 | 0.58 | PDPK1 (0.45) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL28484767 | 0.58 | PDPK1 (0.45) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL3860724 | 0.58 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL30678334 | 0.57 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL2482578 | 0.52 | PDPK1 (0.61) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL588905 | 0.52 | TDP1 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL16418573 | 0.51 | NPSR1 (0.56) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975910-B2 | Hetero-fused cyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |