Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833808 | 0.82 | RPS6KA3 (0.35) | — | |
| SCHEMBL12749936 | 0.76 | NOS3 (0.36) | — | |
| SCHEMBL20169683 | 0.72 | NOS3 (0.32) | — | |
| SCHEMBL18068017 | 0.72 | RPS6KA3 (0.38) | — | |
| SCHEMBL18791405 | 0.72 | NOS3 (0.32) | — | |
| SCHEMBL17866987 | 0.71 | ESR1 (0.33) | TSHR | |
| SCHEMBL24885938 | 0.70 | — | — | |
| SCHEMBL18929769 | 0.70 | — | — | |
| SCHEMBL22191949 | 0.68 | — | — | |
| SCHEMBL12654045 | 0.68 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975896-B2 | Inhibitors of transcription factors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-22 | — | — | US | disclosed |