Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056971 | 0.82 | MASP2 (0.67) | MASP2RAB9AMETAP2LTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL4053943 | 0.81 | MASP2 (0.65) | MASP2RAB9AMETAP2LTA4HALDH1A1 | |
| SCHEMBL19501567 | 0.79 | MASP2 (0.62) | MASP2ADORA1METAP2LTA4HMAP4K4 | |
| SCHEMBL20169739 | 0.79 | MASP2 (0.62) | MASP2NPY5RMETAP2LTA4HSCN4A | |
| SCHEMBL16324218 | 0.79 | NPY5R (0.60) | MASP2NPY5RADORA1LTA4HKMT2A | |
| SCHEMBL18122015 | 0.78 | NPY5R (0.73) | NPY5RSCN2A | |
| SCHEMBL725351 | 0.77 | MASP2 (1.00) | MASP2NPY5RRAB9ALTA4HSCN9A | |
| SCHEMBL19513444 | 0.76 | MASP2 (0.57) | MASP2NPY5RXDHADORA1IDO1 | |
| SCHEMBL13664752 | 0.75 | MASP2 (0.53) | MASP2LTA4HSCN4ASCN9ASCN3A | |
| SCHEMBL18122012 | 0.75 | NPY5R (0.68) | NPY5RRAB9ANPC1SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |