Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.62 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056971 | 0.82 | MASP2 (0.67) | MASP2METAP2LTA4HSCN9ASCN4A | |
| Hydrochloric Acid SCHEMBL4053943 | 0.81 | MASP2 (0.65) | MASP2METAP2LTA4HSCN9ASCN4A | |
| SCHEMBL20169745 | 0.79 | MASP2 (0.62) | MASP2METAP2LTA4HSCN9ASCN4A | |
| SCHEMBL19501567 | 0.79 | MASP2 (0.62) | MASP2METAP2LTA4HSCN9ASCN4A | |
| SCHEMBL20169742 | 0.78 | MASP2 (0.66) | MASP2METAP2LTA4HSCN9ASCN3A | |
| SCHEMBL725351 | 0.77 | MASP2 (1.00) | MASP2LTA4HSCN9ASCN2ANPY5R | |
| SCHEMBL16324218 | 0.76 | NPY5R (0.60) | MASP2LTA4HSCN2ANPY5RKCNH2 | |
| SCHEMBL19513444 | 0.76 | MASP2 (0.57) | MASP2NPY5R | |
| SCHEMBL4063091 | 0.74 | MASP2 (0.56) | MASP2SCN9ASCN4ASCN3AMAPK13 | |
| SCHEMBL13655229 | 0.74 | MASP2 (0.92) | MASP2LTA4HSCN9ASCN2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |