Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 19/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614003 | 1.00 | KDM4E (0.53) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL16614004 | 0.83 | NR3C1 (0.42) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068222 | 0.83 | NR3C1 (0.42) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20169789 | 0.80 | KDM4E (0.38) | KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL20068223 | 0.79 | NR3C1 (0.41) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068224 | 0.79 | NR3C1 (0.39) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068225 | 0.79 | NR3C1 (0.39) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068185 | 0.79 | NR3C1 (0.40) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068220 | 0.79 | NR3C1 (0.40) | KDM4EMEN1KMT2ANPSR1NR3C1 | |
| SCHEMBL20068221 | 0.79 | NR3C1 (0.52) | KDM4EMEN1KMT2ANPSR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975918-B2 | Highly potent glucocorticoids | VAN ANDEL RESEARCH INSTITUTE (US) | 2018-05-22 | — | — | US | disclosed |