Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747742 | 0.88 | HPGD (0.78) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL8490672 | 0.88 | HPGD (0.64) | SMN1; SMN2LMNAMAPK1HPGDRAB9A | |
| SCHEMBL11655759 | 0.86 | SMN1; SMN2 (0.80) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL10658594 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL7565149 | 0.85 | MAPK1 (0.81) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL30444110 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL699052 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL7309848 | 0.84 | PARP1 (0.64) | MAPK1RAB9ACYP1A2ALDH1A1KMT2A | |
| SCHEMBL882828 | 0.84 | RAB9A (0.72) | SMN1; SMN2LMNAMAPK1MAPTHPGD | |
| SCHEMBL832082 | 0.84 | RAB9A (0.64) | SMN1; SMN2LMNAMAPK1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9974859-B2 | Nanostructured gels capable of controlled release of entrapped agents | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2018-05-22 | — | — | US | disclosed |