Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170522 | 0.79 | PKM (0.36) | NOTUM | |
| SCHEMBL19969059 | 0.78 | NOTUM (0.39) | NOTUM | |
| SCHEMBL17018501 | 0.73 | CASR (0.36) | — | |
| SCHEMBL19969081 | 0.73 | NOTUM (0.37) | NOTUM | |
| SCHEMBL18736480 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL19969084 | 0.72 | ALDH1A1 (0.56) | NOTUM | |
| SCHEMBL16561751 | 0.71 | PKM (0.38) | — | |
| SCHEMBL19969061 | 0.68 | POLB (0.43) | NOTUM | |
| SCHEMBL20170557 | 0.67 | HDAC8 (0.40) | — | |
| SCHEMBL20170521 | 0.67 | HDAC8 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041828-B1 | 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-05-23 | — | — | EP | disclosed |