Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170598 | 0.82 | OPRM1 (0.38) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL20170804 | 0.81 | OPRM1 (0.41) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL20170771 | 0.80 | OPRM1 (0.40) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12944958 | 0.74 | OPRD1 (0.43) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL20170597 | 0.74 | OPRD1 (0.43) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12944957 | 0.72 | OPRM1 (0.42) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL20170708 | 0.72 | OPRM1 (0.42) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12646374 | 0.71 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL21202045 | 0.71 | OPRD1 (0.56) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL18457908 | 0.71 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |