Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20825137 | 0.80 | KMT2A (0.32) | — | |
| SCHEMBL18599678 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10357932 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL18951468 | 0.73 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL5580145 | 0.72 | FFAR3 (0.31) | LMNASIGMAR1 | |
| SCHEMBL13957201 | 0.71 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL10697431 | 0.71 | FPR3 (0.33) | LMNA | |
| SCHEMBL14228662 | 0.70 | CNR1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL30695179 | 0.70 | ALDH1A1 (0.39) | SIGMAR1USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL28729089 | 0.69 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772480-B2 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2020-12-09 | — | — | EP | disclosed |
| EP-2772480-B1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2018-05-23 | — | — | EP | disclosed |