Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 18/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373114 | 0.75 | DRD1 (0.52) | TRPA1DRD1HPGDSMN1; SMN2 | |
| SCHEMBL15688588 | 0.72 | TRPA1 (0.51) | TRPA1DRD1 | |
| SCHEMBL15688267 | 0.72 | DRD1 (0.63) | TRPA1DRD1 | |
| SCHEMBL19371701 | 0.69 | DRD1 (0.60) | TRPA1DRD1 | |
| SCHEMBL15688563 | 0.69 | DRD1 (0.59) | TRPA1DRD1 | |
| SCHEMBL29616683 | 0.68 | DRD1 (0.49) | TRPA1DRD1 | |
| SCHEMBL15688472 | 0.68 | DRD1 (0.49) | TRPA1DRD1 | |
| SCHEMBL15688482 | 0.67 | DRD1 (0.55) | TRPA1DRD1 | |
| SCHEMBL23969546 | 0.67 | DRD1 (0.48) | TRPA1DRD1 | |
| SCHEMBL29616769 | 0.67 | DRD1 (0.48) | TRPA1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323821-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | Pfizer Inc (US) | 2018-05-23 | — | — | EP | disclosed |