SCHEMBL948990

SCHEMBL948990

O=C(O)CN1CCCC1=O

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
HTT P42858 1/20 0.57
KMT2A Q03164 2/20 0.55
ALDH1A1 P00352 2/20 0.49
PIK3CD O00329 1/20 0.48
ACE P12821 1/20 0.47
LMNA P02545 2/20 0.47
BLM P54132 1/20 0.46
POLB P06746 1/20 0.45
CYP1A2 P05177 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
CHRM3 P20309 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948880 0.94 TSHR (0.60) TSHRHTTKMT2AALDH1A1PIK3CD
SCHEMBL596327 0.92 TSHR (0.58) TSHRHTTKMT2AALDH1A1PIK3CD
SCHEMBL11036951 0.92 TSHR (0.58) TSHRHTTKMT2AALDH1A1PIK3CD
SCHEMBL6361223 0.86 TSHR (0.50) TSHRHTTKMT2AALDH1A1ACE
SCHEMBL43400 0.86
SCHEMBL7979583 0.86 TSHR (0.53) TSHRHTTKMT2AALDH1A1PIK3CD
SCHEMBL21958786 0.82 TSHR (0.49) TSHRHTTKMT2AALDH1A1ACE
Piracetam SCHEMBL6140872 0.81 TSHR (1.00) TSHRHTTKMT2AALDH1A1PIK3CD
Piracetam SCHEMBL20172 0.81 TSHR (1.00) TSHRHTTKMT2AALDH1A1PIK3CD
SCHEMBL7601362 0.81 TSHR (0.60) TSHRHTTKMT2AALDH1A1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116183763-A9 Impurity detection method of piracetam injection 北京星昊盈盛药业有限公司 2024-01-05 CN claimed
EP-3360533-B1 PATCH FOR TOOTH ATTACHMENT ABLE TO BE REMOVED BY TOOTH BRUSHING LG HOUSEHOLD & HEALTH CARE LTD (KR) 2023-07-26 EP claimed
CN-116183763-A Impurity detection method of piracetam injection 北京星昊盈盛药业有限公司 2023-05-30 CN claimed
CN-115754113-A Method for detecting content of catalyst tetrabutylammonium bromide in piracetam intermediate and finished product through high performance liquid chromatography 东北制药集团股份有限公司 2023-03-07 CN claimed
CN-109988092-B Preparation method of nefiracetam for treating Alzheimer disease 深圳市第二人民医院 2021-11-16 CN claimed
WO-2020216146-A1 PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE 浙江华海药业股份有限公司 2020-10-29 WO claimed
CN-106349144-B A kind of preparation method of (S)-oxiracetam intermediate 山东默得森生物制药有限公司 2019-05-24 CN claimed
CN-109721577-A A kind of purification process of furans dicarboxylic acids 中国科学院宁波材料技术与工程研究所 2019-05-07 CN claimed
CN-106397294-B A kind of preparation method of nootropics (S)-Oxiracetam 山东默得森生物制药有限公司 2019-02-15 CN claimed
CN-107493648-A A kind of sparking electrode for being used to sterilize and preparation method thereof 中金瑞峰资本管理有限公司 2017-12-19 CN claimed
US-6465009-B1 WATER SOLUBLE POLYVINYLPYRROLIDONE, NO SOLVENT, SACCHARIDE OF LOW MOLDABILITY; COMPRESSING, HUMIDIFYING, DRYING YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 2002-10-15 US claimed
EP-1063972-A1 POLYMER BASED RAPIDLY DISSOLVING TABLETS AND PRODUCTION PROCESSES THEREOF Yamanouchi Shaklee Pharma (US) 2001-01-03 EP claimed
WO-1999047126-A1 POLYMER BASED RAPIDLY DISSOLVING TABLETS AND PRODUCTION PROCESSES THEREOF YAMANOUCHI SHAKLEE PHARMA (US) 1999-09-23 WO claimed
US-5267532-A pH-indicating material and cat litter containing same ANITOX CORPORATION (US) 1993-12-07 US claimed
EP-0569232-A1 pH-indicating material and cat litter containing same ANITOX CORPORATION (US) 1993-11-10 EP claimed
WO-1992002498-A1 COMPOUNDS HAVING COGNITION ENHANCER ACTIVITY, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PULITZER ITALIANA S.R.L. (IT) 1992-02-20 WO claimed
EP-0089901-B1 NEW 2-OXO-1-PYRROLIDINEACETIC ACID ESTERS, THEIR METHODS OF PRODUCTION AND THERAPEUTIC COMPOSITIONS CONTAINING THE SAME PRODES S.A. (ES) 1987-05-13 EP claimed
EP-0089901-A1 New 2-oxo-1-pyrrolidineacetic acid esters, their methods of production and therapeutic compositions containing the same PRODES S.A. (ES) 1983-09-28 EP claimed
US-4324787-A 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use TROPONWERKE GMBH & CO., KG (DE) 1982-04-13 US claimed
EP-0003029-B1 NEW 2-OXO-1-PYRROLIDINE ACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION Troponwerke GmbH & Co. KG (DE) 1980-12-10 EP claimed