Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20977474 | 0.84 | SYK (0.47) | SYKKCNH2SCN5ASCN9ATDO2 | |
| SCHEMBL20172003 | 0.83 | NPC1 (0.53) | SYKKCNH2SCN5ASCN9AGRM5 | |
| SCHEMBL15584301 | 0.81 | SYK (0.51) | SYKCHEK1MAPK9MAPK10NPC1 | |
| SCHEMBL20172050 | 0.81 | SYK (0.51) | SYKCHEK1MAPK9MAPK10NPC1 | |
| SCHEMBL16450162 | 0.79 | SYK (0.58) | SYKCHEK1MAPK9MAPK10NPC1 | |
| SCHEMBL15585199 | 0.77 | FLT3 (0.58) | SYKCHEK1STK17BSTK17A | |
| SCHEMBL15584691 | 0.77 | SYK (0.42) | SYKKCNH2SCN5ASCN9AGRM5 | |
| Hydrochloric Acid SCHEMBL21046222 | 0.77 | FLT3 (0.57) | SYKCHEK1STK17BSTK17A | |
| Hydrochloric Acid SCHEMBL7420508 | 0.76 | LOXL2 (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15585214 | 0.74 | SYK (0.52) | SYKNPC1RAB9ASTK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-A1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM Corporation (JP) | 2018-05-23 | — | — | EP | disclosed |