Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20172004 | 0.84 | SYK (0.48) | SYKGRM5MAOBABCG2CYP11B2 | |
| SCHEMBL8877872 | 0.77 | CYP2A6 (0.50) | KCNH2ALDH1A1 | |
| SCHEMBL27637976 | 0.76 | SYK (0.56) | SYKGRM5MAOBMEN1KMT2A | |
| SCHEMBL20172044 | 0.74 | FLT3 (0.54) | SYKGRM5MAOBABCG2FLT3 | |
| SCHEMBL20129536 | 0.72 | FLT3 (0.60) | SYKGRM5MAOBABCG2FLT3 | |
| SCHEMBL20152451 | 0.72 | TSHR (0.50) | CYP11B2KDM4EALDH1A1 | |
| SCHEMBL28610259 | 0.72 | SYK (0.51) | SYKGRM5MAOBABCG2CYP11B2 | |
| SCHEMBL15584131 | 0.70 | FLT3 (0.60) | SYKABCG2FLT3ABCB1ABCC1 | |
| SCHEMBL1741981 | 0.70 | KCNH2 (0.55) | SYKABCG2MEN1KMT2AKCNH2 | |
| SCHEMBL22578800 | 0.69 | KDR (0.55) | SYKFLT3KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-B1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2019-05-08 | — | — | EP | disclosed |