Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20172125 | 0.86 | MEN1 (0.38) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL16482063 | 0.81 | NPC1 (0.44) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL15835963 | 0.81 | NPC1 (0.44) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL15835964 | 0.81 | NPC1 (0.44) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL15317423 | 0.79 | PIM1 (0.47) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL16482065 | 0.79 | NPC1 (0.40) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL15889096 | 0.79 | NPC1 (0.40) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL17490121 | 0.79 | NPC1 (0.58) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL3661706 | 0.79 | ALDH1A1 (0.54) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL13509561 | 0.79 | NPC1 (0.41) | NPC1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980182-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2018-05-23 | — | — | EP | disclosed |