SCHEMBL2017250

SCHEMBL2017250

O=C(O)C(O)C(O)C(O)CCCO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
TSHR P16473 2/20 0.46
CYP2C9 P11712 1/20 0.46
LMNA P02545 1/20 0.34
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
PTPN1 P18031 2/20 0.33
OR51E2 Q9H255 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PGD P52209 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8984391 0.91 PDE4A (0.48) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL3175311 0.91 PDE4A (0.48) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL7172292 0.91 PDE4A (0.48) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL28006023 0.90 PDE4A (0.47) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL28150369 0.90 PDE4A (0.47) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL28005773 0.90 PDE4A (0.47) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL28018004 0.90 PDE4A (0.47) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL7457792 0.86 PDE4A (0.56) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL5484358 0.86 PDE4A (0.44) PDE4ATSHRCYP2C9LMNAUSP2
SCHEMBL1895971 0.86 PDE4A (0.56) PDE4ATSHRCYP2C9LMNAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2025-04-24 US disclosed
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo ENGENE, INC. (CA) 2024-09-03 US disclosed
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2022-05-05 US disclosed
EP-3970697-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO Engene, Inc. (CA) 2022-03-23 EP disclosed
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo HERCULES CAPITAL, INC. 2021-11-09 US disclosed
EP-3049473-B1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO ENGENE INC (CA) 2021-09-22 EP disclosed
US-20200061208-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2020-02-27 US disclosed
US-10456481-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo HERCULES CAPITAL, INC. 2019-10-29 US disclosed
US-20180344875-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2018-12-06 US disclosed
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2016-08-18 US disclosed
EP-3049473-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO Engene, Inc. (CA) 2016-08-03 EP disclosed
WO-2015042711-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO ENGENE, INC. (CA) 2015-04-02 WO disclosed
US-20110160036-A1 VALVE METAL OXIDE FORMULATION H.C. STARCK GMBH (DE) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200061208-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-20180344875-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-10456481-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.