Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895841 | 0.89 | ALDH1A1 (0.64) | HTR1BHTR1DL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL2903634 | 0.89 | L3MBTL1 (0.56) | HTR1BL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16933991 | 0.87 | LMNA (0.62) | L3MBTL1ALDH1A1SMN1; SMN2MEN1USP2 | |
| SCHEMBL12377087 | 0.86 | L3MBTL1 (0.57) | HTR1BHTR1DL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12377085 | 0.84 | HTR1B (0.60) | HTR1BHTR1DL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL19043546 | 0.83 | MEN1 (0.63) | ALDH1A1SMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL18896254 | 0.83 | LMNA (0.61) | L3MBTL1ALDH1A1SMN1; SMN2MEN1USP2 | |
| SCHEMBL2910101 | 0.82 | ACACB (0.56) | HTR1BHTR1DL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17060454 | 0.82 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL17060482 | 0.82 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323812-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | Parion Sciences, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |