Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127151 | 0.82 | KDM4E (0.56) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL17226263 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL18385057 | 0.80 | KDM4E (0.53) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL23343610 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL18327034 | 0.76 | KDM4E (0.47) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL18016432 | 0.75 | HPGDS (0.47) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL11932351 | 0.75 | KDM4E (0.42) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL13003243 | 0.75 | KDM4E (0.42) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL22109949 | 0.74 | TP53 (0.36) | SMN1; SMN2KDM4ELMNATP53HTT | |
| SCHEMBL21396886 | 0.74 | CYP2A6 (0.54) | SMN1; SMN2KDM4ELMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2551932-B1 | Host materials for phosphorescent oleds | UNIVERSAL DISPLAY CORP (US) | 2018-05-23 | — | — | EP | disclosed |