Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21973182 | 0.88 | KDM4E (0.37) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL127151 | 0.85 | KDM4E (0.56) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL18385057 | 0.83 | KDM4E (0.53) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL20172602 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL18327034 | 0.78 | KDM4E (0.47) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL18016432 | 0.77 | HPGDS (0.47) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL21396886 | 0.76 | CYP2A6 (0.54) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL7116753 | 0.75 | KDM4E (0.46) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL23343610 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ELMNACCR1CCR5 | |
| SCHEMBL22109949 | 0.75 | TP53 (0.36) | SMN1; SMN2KDM4ELMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940098-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2015-11-04 | — | — | EP | disclosed |