Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | FURIN | P09958 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16946400 | 0.90 | CA2 (0.53) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL17541381 | 0.89 | CA2 (0.50) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL17541380 | 0.89 | CA2 (0.50) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL23880504 | 0.89 | CA2 (0.51) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL17541357 | 0.87 | CA2 (0.47) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL17541356 | 0.87 | CA2 (0.47) | CA1CA2FURINMAPTTDP1 | |
| SCHEMBL17902993 | 0.87 | CA2 (0.46) | CA1CA2FURINMMP1MMP3 | |
| SCHEMBL20158426 | 0.87 | CA2 (0.46) | CA1CA2FURINMMP1MMP3 | |
| SCHEMBL14012279 | 0.87 | CA2 (0.46) | CA1CA2FURINMMP1MMP3 | |
| SCHEMBL12283259 | 0.87 | CA2 (0.46) | CA1CA2FURINMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20180140714-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180140714-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | FCGR2A, FCGRT, FCGR1A | CA1 2758/4885CA2 4520/4885FURIN 600/4885 |
| US-20180140714-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | FCGR2A, FCGRT, FCGR1A | CA1 2758/4885CA2 4520/4885FURIN 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.