Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169137 | 0.87 | NPC1 (0.74) | EPHX1ALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL730314 | 0.84 | ALDH1A1 (0.80) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL557621 | 0.82 | NPC1 (0.73) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL9317189 | 0.80 | NPC1 (0.70) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL9317188 | 0.80 | NPC1 (0.70) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL11178380 | 0.80 | EPHX1 (0.62) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| N-(Phenylcarbamothioyl)Benzamide SCHEMBL2341910 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL20178974 | 0.80 | NPC1 (0.50) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL3063667 | 0.80 | NPC1 (0.50) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 | |
| SCHEMBL3062971 | 0.79 | POLB (0.54) | EPHX1ALDH1A1TAS2R38HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142322-A1 | METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS | UNIVERSITY OF SASKATCHEWAN (CA) | 2018-05-24 | — | — | US | disclosed |
| US-20180142322-A1 | METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS | UNIVERSITY OF SASKATCHEWAN (CA) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180142322-A1 | METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS | AOC1, SOD1, SLC39A7 | EPHX1 2676/4885ALDH1A1 114/4885TAS2R38 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.