Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256329 | 0.87 | CA12 (0.44) | CA12CA1CA2CA9PPARD | |
| SCHEMBL20174135 | 0.85 | CA12 (0.49) | CA12CA1CA2CA9PPARD | |
| SCHEMBL18248535 | 0.83 | CA12 (0.41) | CA12CA1CA2CA9PPARD | |
| SCHEMBL20174136 | 0.81 | MEN1 (0.59) | CA12CA1CA2CA9PPARD | |
| SCHEMBL4229904 | 0.78 | CA12 (0.51) | CA12CA1CA2CA9PPARD | |
| SCHEMBL14679027 | 0.76 | MEN1 (0.55) | CA12CA1CA2CA9PPARD | |
| SCHEMBL18256330 | 0.75 | CASP2 (0.56) | CA12CA1CA2CA9PPARD | |
| SCHEMBL7268189 | 0.75 | PPARD (0.64) | PPARDTSHR | |
| SCHEMBL11699849 | 0.74 | CA12 (0.50) | CA12CA1CA2CA9PPARD | |
| SCHEMBL11323349 | 0.73 | PPARD (0.61) | PPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SPINT2, SERPINB1 | CA12 2008/4885CA1 1711/4885CA2 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.