Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | FAAH | O00519 | 4/20 | 0.61 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590102 | 0.94 | MEN1 (0.67) | MEN1KMT2AFAAHCASP2EPHX2 | |
| SCHEMBL18248661 | 0.86 | FAAH (0.84) | FAAHCASP2EPHX2NAAADNM1 | |
| SCHEMBL14946400 | 0.86 | FAAH (0.84) | FAAHCASP2EPHX2NAAADNM1 | |
| SCHEMBL19544668 | 0.86 | MEN1 (0.68) | MEN1KMT2AFAAHCASP2EPHX2 | |
| SCHEMBL17860105 | 0.85 | KMT2A (0.58) | MEN1KMT2AFAAHCASP2NAAA | |
| SCHEMBL12673154 | 0.85 | KMT2A (0.58) | MEN1KMT2AFAAHCASP2EPHX2 | |
| SCHEMBL9618659 | 0.84 | FAAH (0.81) | MEN1KMT2AFAAHCASP2EPHX2 | |
| SCHEMBL17229157 | 0.84 | MEN1 (1.00) | MEN1KMT2AFAAHCASP2NAAA | |
| SCHEMBL19731479 | 0.84 | FAAH (0.57) | MEN1KMT2AFAAHCASP2EPHX2 | |
| SCHEMBL14500856 | 0.84 | FAAH (0.62) | MEN1KMT2AFAAHCASP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SPINT2, SERPINB1 | MEN1 1836/4885KMT2A 1097/4885FAAH 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.