Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174284 | 0.95 | PDK2 (0.39) | PDK2ADORA3KMT2AMAPK1MYC | |
| SCHEMBL20174248 | 0.93 | KMT2A (0.35) | PDK2ENPP3ALOX5KMT2AMAPK1 | |
| SCHEMBL20174199 | 0.93 | PDK2 (0.36) | PDK2ADORA3KMT2AMAPK1MEN1 | |
| SCHEMBL20174209 | 0.92 | PDK2 (0.36) | PDK2ENPP3KMT2AMAPK1MEN1 | |
| SCHEMBL22326538 | 0.91 | PDK2 (0.33) | PDK2ENPP3ALOX5KMT2AMAPK1 | |
| SCHEMBL20174243 | 0.91 | PDK2 (0.33) | PDK2ENPP3ALOX5KMT2AMAPK1 | |
| SCHEMBL20174201 | 0.89 | ALOX5 (0.32) | PDK2ENPP3ALOX5KMT2AMAPK1 | |
| SCHEMBL20174271 | 0.89 | CYP1A1 (0.37) | PDK2KMT2AMAPK1 | |
| SCHEMBL20174244 | 0.89 | ALDH1A1 (0.33) | ENPP3KMT2AMAPK1 | |
| SCHEMBL20174214 | 0.88 | PDK2 (0.36) | PDK2ENPP3ADORA3KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885ENPP3 3214/4885ALOX5 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.