Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477358 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL8722507 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL15735445 | 0.75 | ACHE (0.41) | SMN1; SMN2PARP1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL2021132 | 0.75 | ESR1 (0.39) | ALDH1A1GAAKDM4E | |
| SCHEMBL23457112 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2GAAC1S | |
| SCHEMBL783254 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2GAAC1S | |
| SCHEMBL29945235 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2GAAC1S | |
| SCHEMBL4876931 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2C1SPARP1 | |
| SCHEMBL10928549 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2GAAC1S | |
| SCHEMBL21263582 | 0.71 | NPC1 (0.45) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341108-B1 | Surface treatment method for solid material | SHINETSU CHEMICAL CO (JP) | 2014-07-02 | — | — | EP | disclosed |
| US-8541631-B2 | Surface treatment method for solid material | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-2341108-A1 | Surface treatment method for solid material | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-07-06 | — | — | EP | disclosed |
| US-20110160464-A1 | SURFACE TREATMENT METHOD FOR SOLID MATERIAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160464-A1 | SURFACE TREATMENT METHOD FOR SOLID MATERIAL | H1-2, H1-0, HRH3 | ALDH1A1 4154/4885MAPK1 4356/4885SMN1; SMN2 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.