Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174698 | 0.93 | PDK2 (0.47) | PDK2APPCYP2C9ERN1MAPT | |
| SCHEMBL20175215 | 0.78 | PDK2 (0.40) | PDK2APPAKR1A1AKR1B1ERN1 | |
| SCHEMBL20175199 | 0.77 | PDK2 (0.41) | PDK2AKR1A1AKR1B1MAOBDRD2 | |
| SCHEMBL19167331 | 0.75 | PDK2 (0.49) | PDK2MAPTMDM2 | |
| SCHEMBL19167901 | 0.75 | PDK2 (0.49) | PDK2MAPTMDM2 | |
| SCHEMBL20174708 | 0.74 | PDK2 (0.46) | PDK2APPCYP2C9ERN1MAPT | |
| SCHEMBL20175211 | 0.74 | CYP2A6 (0.41) | APPCYP2C9ERN1MAPTMAOB | |
| SCHEMBL20373828 | 0.74 | PDK2 (0.54) | PDK2MAPT | |
| SCHEMBL20687371 | 0.74 | PDK2 (0.54) | PDK2AKR1A1AKR1B1 | |
| SCHEMBL20199303 | 0.74 | PDK2 (0.35) | PDK2APPCYP2C9ERN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, NR2E3, ALDH1A2 | PDK2 580/4885APP 2250/4885CYP2C9 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.