Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319555 | 0.81 | ERN1 (0.42) | CYP2A6APPCYP2C9ERN1MAPT | |
| SCHEMBL20174709 | 0.79 | CYP2A6 (0.42) | CYP2A6APPCYP2C9ERN1MAPT | |
| SCHEMBL4381193 | 0.76 | CYP2A6 (0.54) | CYP2A6APPCYP2C9ERN1MAPT | |
| SCHEMBL10015032 | 0.75 | S100A4 (0.38) | CYP2A6KDM4EMAPT | |
| SCHEMBL20599056 | 0.74 | S100A4 (0.46) | CYP2A6LMNATP53 | |
| SCHEMBL9565764 | 0.74 | ERN1 (0.49) | CYP2A6ERN1MAPTCHRM2CHRM4 | |
| SCHEMBL20175214 | 0.74 | PDK2 (0.41) | CYP2A6APPCYP2C9ERN1MAPT | |
| SCHEMBL18731804 | 0.74 | ALOX5 (0.47) | KDM4EMAPTTP53MAOB | |
| SCHEMBL18034336 | 0.74 | KDM4E (0.45) | KDM4EMAPTMAOB | |
| SCHEMBL17068901 | 0.73 | S100A4 (0.47) | CYP2A6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, NR2E3, ALDH1A2 | CYP2A6 265/4885APP 2250/4885CYP2C9 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.