Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127234 | 0.92 | PIK3CG (0.61) | SIRT1KMT2ARAB9ANPC1POLB | |
| SCHEMBL6570129 | 0.90 | KDM1A (0.58) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL6570128 | 0.90 | KDM1A (0.58) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28515473 | 0.89 | SIRT1 (0.70) | SIRT1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL12746380 | 0.88 | MEN1 (0.58) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL684769 | 0.88 | KDM1A (0.66) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL684835 | 0.87 | KDM1A (0.72) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL12746377 | 0.85 | SIRT1 (0.72) | SIRT1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8343578 | 0.85 | SIRT1 (0.85) | SIRT1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8343583 | 0.85 | SIRT1 (0.85) | SIRT1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | SIRT1 3490/4885KMT2A 3034/4885MEN1 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.