Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.66 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22367607 | 0.91 | KMT2A (0.62) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL21145694 | 0.91 | KMT2A (0.62) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL21145692 | 0.91 | KMT2A (0.62) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL15127234 | 0.89 | PIK3CG (0.61) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL685021 | 0.89 | KDM1A (0.61) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL683817 | 0.89 | KDM1A (0.68) | KDM1APIK3CGKMT2AHTTSMN1; SMN2 | |
| SCHEMBL27178065 | 0.88 | RAB9A (0.63) | KDM1AKMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL27178059 | 0.88 | RAB9A (0.63) | KDM1AKMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL30826069 | 0.88 | RAB9A (0.63) | KDM1AKMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL20175461 | 0.87 | SIRT1 (0.64) | KDM1AKMT2AHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | THE GENERAL HOSPITAL CORPORATION | 2021-08-05 | — | — | US | disclosed |
| US-8791298-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8791298-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130281353-A1 | Use of Metal Hydrazide Complex Compounds as Oxidation Catalysts | BASF SE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281353-A1 | Use of Metal Hydrazide Complex Compounds as Oxidation Catalysts | BASF SE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8492324-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-8492324-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110071066-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071066-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | SOD1, H1-4, H1-5 | KDM1A 505/4885PIK3CG 3391/4885KMT2A 453/4885 |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | KDM1A 484/4885PIK3CG 2876/4885KMT2A 1362/4885 |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | MPL, CSF3R, CSF1R | KDM1A 2673/4885PIK3CG 1929/4885KMT2A 887/4885 |
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | G3BP1, G3BP2, HMGB2 | KDM1A 2810/4885PIK3CG 2805/4885KMT2A 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.