SCHEMBL20175594

SCHEMBL20175594

c1ccc(-n2c3ccccc3c3cc(-c4cc5sc6ccccc6c5c5c4c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.33
▸ PTGER4 P35408 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20175602 0.97 L3MBTL1 (0.39) ATMKDM4EL3MBTL1HSD17B10PTGER4
SCHEMBL20175625 0.97 L3MBTL1 (0.39) ATMKDM4EL3MBTL1HSD17B10PTGER4
SCHEMBL20175601 0.95 KDM4E (0.37) ATMKDM4EL3MBTL1HDAC4
SCHEMBL20175620 0.94 KDM4E (0.37) ATMKDM4EL3MBTL1
SCHEMBL20175613 0.94 KDM4E (0.37) ATMKDM4EL3MBTL1
SCHEMBL20175607 0.93 ATM (0.42) ATMKDM4EL3MBTL1HSD17B10MEN1
SCHEMBL20175624 0.93 KDM4E (0.36) ATMKDM4EL3MBTL1HDAC4
SCHEMBL20175615 0.93 KDM4E (0.36) ATMKDM4EL3MBTL1HDAC4
SCHEMBL20175616 0.92 KDM4E (0.35) ATMKDM4EL3MBTL1
SCHEMBL20175621 0.92 KDM4E (0.35) ATMKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266787-B1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-07-06 — — EP disclosed
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS MERCK PATENT GMBH (DE) 2022-01-20 — — US disclosed
WO-2020085793-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-04-30 — — WO disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS AZI2, OCIAD2, SELP ATM 4429/4885KDM4E 2006/4885L3MBTL1 3961/4885
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 ATM 4361/4885KDM4E 1121/4885L3MBTL1 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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