Sugi Predict

Sugi Predict / Compounds / SCHEMBL20175679

SCHEMBL20175679

SCHEMBL20175679

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5cc6c7ccccc7n(-c7ccccc7)c6c6c5oc5ccccc56)ccc43)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.40
▸ ATM Q13315 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.34
▸ POLB P06746 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ BRCA1 P38398 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ PPARG P37231 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ NR2E3 Q9Y5X4 1/20 0.33
▸ NCOR2 Q9Y618 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ PLA2G2A P14555 1/20 0.33
▸ PLA2G4A P47712 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ CDC14B O60729 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20175676 0.97 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL20175545 0.90 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18594157 0.89 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL20175682 0.88 MAPT (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL20175681 0.87 ALOX5 (0.37) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18594199 0.87 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18101398 0.87 TNKS (0.36) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL19863089 0.87 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL17228930 0.87 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL20382139 0.86 CDC14B (0.33) KDM4EATML3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-07-21 — — US disclosed
WO-2020085793-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-04-30 — — WO disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 KDM4E 1121/4885ATM 4361/4885L3MBTL1 561/4885
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 KDM4E 1121/4885ATM 4361/4885L3MBTL1 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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