Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961008 | 0.78 | CYP1A2 (0.42) | CYP1A2TDP1MGLLPHGDHHTR1A | |
| SCHEMBL18288356 | 0.77 | ALDH1A1 (0.38) | CYP1A2MGLLNPSR1LMNAHPGD | |
| SCHEMBL18288361 | 0.76 | — | — | |
| SCHEMBL26203591 | 0.76 | HRH3 (0.43) | ALDH1A1EPHX2 | |
| SCHEMBL22368188 | 0.75 | ALDH1A1 (0.42) | CYP1A2MGLLPHGDHHPGDALOX15 | |
| SCHEMBL18602166 | 0.73 | PHGDH (0.42) | CYP1A2MGLLPHGDHLMNAHPGD | |
| SCHEMBL19016181 | 0.72 | CYP1A2 (0.46) | CYP1A2TDP1MGLLPHGDHHTR1A | |
| SCHEMBL6840170 | 0.71 | CYP1A2 (0.52) | CYP1A2TDP1HTR1ACHRM1CHRM4 | |
| SCHEMBL19464836 | 0.71 | CYP1A2 (0.41) | CYP1A2TDP1MGLLPHGDHHTR1A | |
| SCHEMBL29322932 | 0.71 | CA2 (0.41) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | RFC3, RFC2, RFC1 | CYP1A2 1753/4885TDP1 2264/4885MGLL 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.