Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175943 | 0.94 | MAPT (0.47) | MAPTHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL20175944 | 0.90 | MAPT (0.43) | MAPTHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL20175934 | 0.89 | BCHE (0.45) | MAPTHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL20175936 | 0.86 | MAPT (0.43) | MAPTHTR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20175938 | 0.85 | BCHE (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL20180914 | 0.84 | HSPA5 (0.48) | HTR1AMEN1KMT2AHSPA5PRKCI | |
| SCHEMBL30589673 | 0.84 | SMN1; SMN2 (0.49) | HTR1ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20175935 | 0.83 | BCHE (0.46) | MAPTHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL17264228 | 0.82 | MAPT (0.50) | MAPTHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL20175931 | 0.81 | ACHE (0.52) | MAPTBCHEACHEHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140581-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140581-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | FECH, SLC19A1, SLC40A1 | MAPT 3805/4885HTR1A 1408/4885SMN1; SMN2 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.