Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CFB | P00751 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883869 | 1.00 | TAAR1 (0.50) | TAAR1POLBLMNACYP2D6ADRA2A | |
| SCHEMBL1784726 | 1.00 | TAAR1 (0.50) | TAAR1POLBLMNACYP2D6ADRA2A | |
| SCHEMBL6368496 | 0.84 | ADRA2A (0.42) | TAAR1POLBLMNACYP2D6ADRA2A | |
| SCHEMBL1788139 | 0.78 | CFB (0.46) | TAAR1POLBCYP2D6ADRA2AADRA2B | |
| SCHEMBL1120232 | 0.76 | ADRA2A (0.41) | TAAR1POLBLMNACYP2D6ADRA2A | |
| SCHEMBL11248212 | 0.76 | ADRA2A (0.41) | TAAR1POLBCYP2D6ADRA2AADRA2B | |
| SCHEMBL13616137 | 0.76 | ADRA2A (0.41) | TAAR1POLBCYP2D6ADRA2AADRA2B | |
| SCHEMBL2019626 | 0.75 | L3MBTL1 (0.49) | POLBCYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL11250505 | 0.74 | ADRA2A (0.40) | TAAR1POLBLMNACYP2D6ADRA2A | |
| SCHEMBL12870235 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256755-A | Method of using N-substituted dihydro-2-oxazolamines as analgesics | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1981-03-17 | — | — | US | claimed |
| US-8221775-B2 | Pyrrolin-2-ylamino compounds for combating animal pests | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| EP-2346822-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | BASF SE | 2011-06-30 | — | — | US | disclosed |
| WO-2010029069-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
| US-4256755-A | Method of using N-substituted dihydro-2-oxazolamines as analgesics | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | RXFP3, CBR3, ATL3 | TAAR1 282/4885POLB 3605/4885LMNA 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.