Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576929 | 0.91 | HTT (0.41) | L3MBTL1HTTKDM4ENPSR1CYP3A4 | |
| SCHEMBL1156686 | 0.88 | CYP1A2 (0.56) | L3MBTL1HTTKDM4ENPSR1CYP3A4 | |
| SCHEMBL3414023 | 0.87 | ADRA2A (0.40) | L3MBTL1HTTKDM4ENPSR1CYP3A4 | |
| SCHEMBL1120243 | 0.80 | ADRA2A (0.39) | KDM4ECYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3415726 | 0.79 | TAAR1 (0.40) | L3MBTL1KDM4ECYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3411854 | 0.78 | ADRA2A (0.37) | KDM4ECYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15727100 | 0.78 | PDE4A (0.38) | L3MBTL1HTTKDM4ENPSR1CYP3A4 | |
| SCHEMBL3415416 | 0.77 | ADRA2A (0.40) | CYP3A4CYP1A2CYP2D6CYP2C9ADRA2A | |
| SCHEMBL4107387 | 0.76 | CFB (0.37) | CYP3A4CYP1A2CYP2D6CYP2C19ADRA2A | |
| SCHEMBL1784726 | 0.75 | TAAR1 (0.50) | L3MBTL1KDM4ECYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221775-B2 | Pyrrolin-2-ylamino compounds for combating animal pests | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| EP-2346822-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | BASF SE | 2011-06-30 | — | — | US | disclosed |
| WO-2010029069-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
| US-7655600-B2 | 4,5-Dihydro-4-methyloxazol-2-yl)-[2-(3-chloro-phenyl)-1-phenyl-ethyl]-amine; 1-[1-(4-Chlorophenyl)-2-phenyl-ethyl]-(4,5-dihydrothiazol-2-yl)-amine; animal pests; agriculture; broad activity spectrum against difficult to control insects etc. | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-02 | — | — | US | disclosed |
| WO-2009120648-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20090239918-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090239918-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090239918-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239918-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ADRB2, ADRA2C, ADRA2A | L3MBTL1 3640/4885HTT 2929/4885KDM4E 3040/4885 |
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | ANXA1, ANTXR2, ANXA2 | L3MBTL1 418/4885HTT 2813/4885KDM4E 2567/4885 |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | RXFP3, CBR3, ATL3 | L3MBTL1 463/4885HTT 2503/4885KDM4E 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.