SCHEMBL20176463

SCHEMBL20176463

c1ccc2cc3c(cc2c1)oc1ccc(-c2ccc(-c4c5ccccc5c(-c5cc6ccccc6c6ccccc56)c5ccccc45)cn2)cc13

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.34
MAPT P10636 4/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 3/20 0.33
GRM4 Q14833 3/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 2/20 0.33
ESR1 P03372 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
NPC1 O15118 1/20 0.32
CCNT1 O60563 1/20 0.31
CCNA2 P20248 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26161286 0.90 GRM4 (0.34) CYP11B1MAPTKMT2AKDM4EGRM4
SCHEMBL20176808 0.88 MAPT (0.39) MAPTKMT2AKDM4EGRM4ALDH1A1
SCHEMBL20176698 0.88 ESR1 (0.40) CYP11B1MAPTKMT2AKDM4EGRM4
SCHEMBL20176712 0.88 AXL (0.34) MAPTKMT2AKDM4EGRM4ALDH1A1
SCHEMBL26161092 0.87 ESR1 (0.40) CYP11B1MAPTKMT2AKDM4EGRM4
SCHEMBL16067993 0.87 ALOX5 (0.36) CYP11B1MAPTKMT2AKDM4EALDH1A1
SCHEMBL20176453 0.85 CCNT1 (0.39) MAPTKMT2AKDM4EGRM4ALDH1A1
SCHEMBL26161267 0.85 CYP11B1 (0.36) CYP11B1GRM4ESR1NPC1CASP3
SCHEMBL20176584 0.85 MAPK14 (0.36) CYP11B1MAPTKDM4EGRM4ALDH1A1
SCHEMBL20176832 0.84 ESR1 (0.37) KMT2AGRM4L3MBTL1ESR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 CYP11B1 836/4885MAPT 668/4885KMT2A 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.