SCHEMBL20176538

SCHEMBL20176538

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc6c(c5)c5ccc7ccccc7c5n6-c5ccccc5)nc4)c4ccccc34)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
MTOR P42345 2/20 0.33
KMT2A Q03164 1/20 0.32
MAPK10 P53779 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PTGES O14684 1/20 0.32
NR3C1 P04150 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26160955 0.99 HSD17B1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26160957 0.97 MTOR (0.34) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL20176513 0.97 MTOR (0.34) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26161223 0.94 NR3C1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26161042 0.94 NR3C1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26161225 0.94 NR3C1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26161040 0.93 HSD17B1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL20176495 0.93 HSD17B1 (0.33) HSD17B1HSD17B2MTORKMT2AMAPK10
SCHEMBL26160954 0.91 HSD17B1 (0.34) HSD17B1HSD17B2MTORKMT2APIK3CD
SCHEMBL26161136 0.86 JAK2 (0.36) HSD17B1HSD17B2MTORKMT2AMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 HSD17B1 1993/4885HSD17B2 2055/4885MTOR 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.