Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891300 | 0.85 | ATM (0.51) | ATMCYP11B1CYP11B2P2RX3SIRT2 | |
| SCHEMBL510630 | 0.85 | ATM (0.54) | ATMCYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL16881291 | 0.85 | P2RX3 (0.50) | ATMCYP11B1CYP11B2P2RX3SIRT2 | |
| SCHEMBL16880686 | 0.84 | ALDH1A1 (0.57) | ATMCYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL16880940 | 0.83 | ATM (0.53) | ATMCYP11B1CYP11B2P2RX3SIRT2 | |
| SCHEMBL10895053 | 0.83 | USP2 (0.53) | MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL20176626 | 0.82 | SIRT2 (0.65) | CYP11B1CYP11B2KMT2ASIRT2SIRT1 | |
| SCHEMBL6132139 | 0.81 | CA1 (0.62) | ATMMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL2885990 | 0.81 | MAPT (0.56) | ATMCYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL13326244 | 0.79 | ATM (0.62) | ATMCYP11B1CYP11B2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092047-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2018-05-24 | — | — | WO | disclosed |