Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17935187 | 0.93 | CA1 (0.59) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL30360089 | 0.93 | CA1 (0.59) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL21790849 | 0.91 | CA1 (0.57) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL21790827 | 0.91 | CA1 (0.63) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL21790848 | 0.88 | CA1 (0.63) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL23617161 | 0.87 | CA1 (0.52) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL21784383 | 0.80 | CA1 (0.44) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL20176655 | 0.80 | ALOX5 (0.40) | CA1CA2GABRA1GABRB2ALOX5 | |
| SCHEMBL21790825 | 0.76 | GABRA1 (0.62) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL17323097 | 0.76 | CA1 (0.81) | CA1CA2GABRA1GABRB2GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | CA1 2497/4885CA2 2753/4885GABRA1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.