Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975468 | 0.91 | ALOX5 (0.44) | ALOX5HMGCRGABRA1GABRB2CA1 | |
| SCHEMBL22958480 | 0.84 | PRKCE (0.40) | ALOX5HMGCRGABRA1GABRB2CA1 | |
| SCHEMBL11612512 | 0.83 | CA1 (0.54) | ALOX5HMGCRGABRA1GABRB2CA1 | |
| SCHEMBL20176653 | 0.80 | CA1 (0.52) | ALOX5HMGCRGABRA1GABRB2CA1 | |
| SCHEMBL18924218 | 0.79 | PTPN1 (0.52) | ALOX5HMGCRTYRPTPN1PTPN11 | |
| SCHEMBL11374001 | 0.79 | HMGCR (0.42) | ALOX5HMGCRMAOAPRKCITYR | |
| SCHEMBL1021760 | 0.79 | AMY1A (0.47) | ALOX5HMGCRGABRA1GABRB2CA2 | |
| SCHEMBL1022126 | 0.79 | PTPN1 (0.47) | ALOX5GABRA1GABRB2PTPN1 | |
| SCHEMBL5140860 | 0.77 | TYR (0.50) | ALOX5MAOATYR | |
| SCHEMBL740548 | 0.77 | AMY1A (0.45) | ALOX5HMGCRGABRA1GABRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | ALOX5 654/4885HMGCR 1193/4885GABRA1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.