Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 5/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036128 | 0.82 | NPC1 (0.50) | NPC1TSHRMEN1KMT2AATM | |
| SCHEMBL8291602 | 0.72 | CA12 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL27187357 | 0.69 | CRBN (0.42) | NPC1TSHRMEN1KMT2AATM | |
| SCHEMBL27422291 | 0.69 | ALOX15 (0.48) | TSHRDGAT1CCR1CCR2RXFP1 | |
| SCHEMBL8296947 | 0.69 | GRIA1 (0.49) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30116166 | 0.68 | ALDH1A1 (0.59) | TSHRMEN1KMT2ACCR1CCR2 | |
| SCHEMBL27380693 | 0.68 | NPC1 (0.35) | NPC1TSHRMEN1KMT2AATM | |
| SCHEMBL17543490 | 0.68 | ALDH1A1 (0.59) | TSHRMEN1KMT2ACCR1CCR2 | |
| SCHEMBL20176617 | 0.67 | KMT2A (0.53) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL29348942 | 0.67 | KDM4E (0.38) | NPC1TSHRMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352276-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2019-11-21 | — | — | US | disclosed |
| WO-2018092047-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352276-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | BTK, ABL1, CNKSR1 | NPC1 1786/4885TSHR 238/4885MEN1 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.