Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21579344 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL20176821 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL20176823 | 0.74 | POLB (0.46) | KDM4EALDH1A1COMTGAAHSD17B10 | |
| SCHEMBL7881481 | 0.66 | KDM4E (0.47) | KDM4EALDH1A1GAA | |
| SCHEMBL21652820 | 0.66 | NPSR1 (0.37) | KDM4EALDH1A1L3MBTL1COMTGAA | |
| SCHEMBL2628992 | 0.65 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL21633972 | 0.64 | CASP3 (0.34) | — | |
| SCHEMBL21652805 | 0.64 | ALDH1A1 (0.37) | KDM4EALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL480289 | 0.62 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL27381160 | 0.61 | KDM4E (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092047-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2018-05-24 | — | — | WO | disclosed |