Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469385 | 0.82 | MAPT (0.32) | MAPT | |
| SCHEMBL24042300 | 0.79 | ERN1 (0.41) | MAPT | |
| SCHEMBL12040540 | 0.74 | DGAT1 (0.31) | — | |
| SCHEMBL24207668 | 0.72 | RAB9A (0.34) | MAPT | |
| SCHEMBL21823376 | 0.71 | ERN1 (0.40) | — | |
| SCHEMBL21368845 | 0.70 | ERN1 (0.35) | — | |
| SCHEMBL30525820 | 0.67 | HDAC1 (0.34) | — | |
| SCHEMBL20600826 | 0.67 | HDAC1 (0.34) | — | |
| SCHEMBL21105184 | 0.67 | — | — | |
| SCHEMBL16546182 | 0.67 | PARP1 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093569-A1 | SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |