Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.31 | |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325038 | 1.00 | DPP4 (0.35) | DPP4PDFCA1CA2CA7 | |
| SCHEMBL19337483 | 0.85 | DPP4 (0.33) | DPP4 | |
| SCHEMBL26378526 | 0.85 | TP53 (0.33) | DPP4 | |
| SCHEMBL12087645 | 0.83 | DPP4 (0.32) | DPP4 | |
| SCHEMBL21758072 | 0.83 | DPP4 (0.32) | DPP4 | |
| SCHEMBL13575235 | 0.80 | DPP4 (0.33) | DPP4 | |
| SCHEMBL13284124 | 0.78 | DPP4 (0.30) | DPP4 | |
| SCHEMBL13821860 | 0.77 | DPP4 (0.35) | DPP4 | |
| SCHEMBL13263592 | 0.77 | PDF (0.31) | ||
| SCHEMBL14108242 | 0.76 | ALDH1A1 (0.38) | DPP4PDFALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968183-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200094542-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE, POLYMER PARTICLE, AND COMPOSITION | FUJIFILM CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| US-10344003-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180141916-A1 | NOVEL SMALL MOLECULE FIEL1 INHIBITOR IN INFLAMMATORY AND FIBROTIC LUNG INJURY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141916-A1 | NOVEL SMALL MOLECULE FIEL1 INHIBITOR IN INFLAMMATORY AND FIBROTIC LUNG INJURY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344003-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | FIP1L1, TRIM28, TFPI2 | DPP4 2423/4885PDF 1545/4885CA1 4868/4885 |
| US-20180141916-A1 | NOVEL SMALL MOLECULE FIEL1 INHIBITOR IN INFLAMMATORY AND FIBROTIC LUNG INJURY | FIP1L1, TRIM28, TFPI2 | DPP4 2632/4885PDF 1572/4885CA1 4864/4885 |
| US-10968183-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | FIP1L1, TRIM28, TFPI2 | DPP4 2423/4885PDF 1545/4885CA1 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.