Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280768 | 0.94 | MAOB (0.46) | MAOBHSD11B1GABRB3SLC9A1ALDH1A1 | |
| SCHEMBL5272831 | 0.85 | GABRB3 (0.41) | MAOBGABRB3 | |
| SCHEMBL24349128 | 0.78 | MAOB (0.51) | MAOBHSD11B1GABRB3MIFSLC9A1 | |
| SCHEMBL25673612 | 0.78 | MAOB (0.51) | MAOBHSD11B1GABRB3MIFSLC9A1 | |
| SCHEMBL5531413 | 0.77 | SCD (0.38) | ALDH1A1 | |
| SCHEMBL5273564 | 0.76 | — | — | |
| SCHEMBL5280965 | 0.76 | SLC9A1 (0.45) | MAOBSLC9A1ALDH1A1 | |
| SCHEMBL5531536 | 0.75 | SCD (0.40) | — | |
| SCHEMBL5541498 | 0.75 | SCD (0.40) | — | |
| SCHEMBL5533758 | 0.75 | SCD (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227476-B1 | METHODS AND KITS FOR THERANOSTIC APPLICATIONS | TRIBIOTICA LLC (US) | 2021-02-24 | — | — | EP | disclosed |
| EP-3004351-B1 | METHODS AND COMPOSITIONS FOR TEMPLATED ASSEMBLY OF NUCLEIC ACID SPECIFIC HETEROCOMPOUNDS | TRIBIOTICA LLC (US) | 2018-08-08 | — | — | EP | disclosed |
| WO-2018094195-A1 | METHODS FOR DIRECTED FOLDING ASSEMBLY OR DIMERIZATION OF PROTEINS BY TEMPLATED ASSEMBLY REACTIONS | TRIBIOTICA LLC (US) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018094070-A1 | METHODS FOR PREVENTING TITRATION OF BIMOLECULAR TEMPLATED ASSEMBLY REACTIONS BY STRUCTURALLY-DETERMINED DIFFERENTIAL HYBRIDIZATIONS | TRIBIOTICA LLC (US) | 2018-05-24 | — | — | WO | disclosed |