Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 0.47 |
| ▸ | FPR1 | P21462 | 15/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177658 | 0.93 | FPR2 (0.48) | FPR2FPR1CYP3A4PKMHTT | |
| SCHEMBL20177604 | 0.91 | FPR2 (0.47) | FPR2FPR1CYP3A4PKMHTT | |
| SCHEMBL20177894 | 0.90 | FPR2 (0.59) | FPR2FPR1CYP3A4 | |
| SCHEMBL20177901 | 0.89 | FPR2 (0.49) | FPR2FPR1CYP3A4NAAAASAH1 | |
| SCHEMBL20177914 | 0.89 | FPR1 (0.43) | FPR2FPR1PKMHTTSMN1; SMN2 | |
| SCHEMBL20177720 | 0.89 | NAAA (0.41) | FPR2FPR1NAAA | |
| SCHEMBL20177629 | 0.87 | FPR2 (0.54) | FPR2FPR1CYP3A4 | |
| SCHEMBL20177677 | 0.85 | FPR1 (0.40) | FPR2FPR1PKMHTTSMN1; SMN2 | |
| SCHEMBL20177949 | 0.85 | FPR1 (0.52) | FPR2FPR1PKMHTTSMN1; SMN2 | |
| SCHEMBL20177900 | 0.83 | FPR2 (0.42) | FPR2FPR1CYP3A4NAAAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |