Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177654 | 0.90 | FPR2 (0.62) | FPR2KCNQ2FPR1MAPT | |
| SCHEMBL20177685 | 0.89 | FPR2 (0.59) | FPR2FPR1MAPT | |
| SCHEMBL20177559 | 0.88 | FPR2 (0.58) | FPR2FPR1 | |
| SCHEMBL20177613 | 0.88 | FPR2 (0.58) | FPR2FPR1LMNAMAPT | |
| SCHEMBL18264293 | 0.86 | FPR2 (0.75) | FPR2FPR1 | |
| SCHEMBL18264295 | 0.86 | FPR2 (0.75) | FPR2FPR1 | |
| SCHEMBL18270452 | 0.85 | FPR2 (0.46) | FPR2CA1CA2ACHEKCNQ2 | |
| SCHEMBL20177944 | 0.81 | FPR2 (0.50) | FPR2FPR1LMNA | |
| SCHEMBL20177886 | 0.81 | FPR2 (0.50) | FPR2KCNQ2LMNAMAPT | |
| SCHEMBL20177719 | 0.81 | FPR2 (0.50) | FPR2KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |