SCHEMBL20177559 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FPR2	P25090	4/20	0.58

▸	PKM	P14618	1/20	0.40

▸	HTT	P42858	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	ENPP2	Q13822	1/20	0.37

▸	FPR1	P21462	6/20	0.36

▸	ALDH1A1	P00352	2/20	0.35

▸	KCNH2	Q12809	1/20	0.35

▸	GRIN2B	Q13224	1/20	0.35

▸	HTR2A	P28223	1/20	0.34

▸	CYP3A4	P08684	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20177654	0.93	FPR2 (0.62)	FPR2PKMHTTSMN1; SMN2FPR1
SCHEMBL20177613	0.92	FPR2 (0.58)	FPR2PKMHTTSMN1; SMN2FPR1
SCHEMBL20177944	0.91	FPR2 (0.50)	FPR2PKMHTTSMN1; SMN2ENPP2
SCHEMBL20177685	0.90	FPR2 (0.59)	FPR2PKMHTTSMN1; SMN2FPR1
SCHEMBL20177520	0.88	FPR2 (0.64)	FPR2FPR1
SCHEMBL20177719	0.88	FPR2 (0.50)	FPR2PKMHTTSMN1; SMN2ENPP2
SCHEMBL20177925	0.87	FPR2 (0.46)	FPR2PKMHTTSMN1; SMN2FPR1
SCHEMBL20177886	0.85	FPR2 (0.50)	FPR2PKMHTTSMN1; SMN2ALDH1A1
SCHEMBL20177489	0.79	FPR2 (0.44)	FPR2PKMHTTSMN1; SMN2
SCHEMBL18264295	0.79	FPR2 (0.75)	FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018092916-A1	NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE	宇部興産株式会社	2018-05-24	—	—	WO	disclosed