Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177654 | 0.93 | FPR2 (0.62) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177559 | 0.92 | FPR2 (0.58) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177886 | 0.91 | FPR2 (0.50) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177685 | 0.90 | FPR2 (0.59) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177520 | 0.88 | FPR2 (0.64) | FPR2FPR1LMNAMAPT | |
| SCHEMBL20177944 | 0.85 | FPR2 (0.50) | FPR2PKMHTTSMN1; SMN2HTR2A | |
| SCHEMBL20177719 | 0.85 | FPR2 (0.50) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177925 | 0.82 | FPR2 (0.46) | FPR2PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20177489 | 0.79 | FPR2 (0.44) | FPR2PKMHTTSMN1; SMN2LMNA | |
| SCHEMBL18264295 | 0.79 | FPR2 (0.75) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |